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. 2019 Nov 18;9:16994. doi: 10.1038/s41598-019-53487-6

Figure 4.

Figure 4

(a) Mean length of microcracks at 4, 12 and 24 weeks in control and animals with type 1 diabetes mellitus. Longer microcracks were found at the 24-week onset of diabetes when compared to the control group [p < 0.05 indicated by (*)] and with 4 and 12-week onset of diabetes p < 0.01 (**) and p < 0.05; respectively (b) Shows crack numerical density (Cr.N.Dn) in controls and rats with 4, 12 and 24 weeks of the onset of type 1 diabetes mellitus. Cr.N.Dn is significantly [p < 0.001 (***)] higher at 4 weeks when compared with control and with 12 weeks [p < 0.05 (*)] and 24 weeks (p < 0.01) duration of diabetes (c) Crack surface density is significantly [p < 0.01 (**)] higher at 4 weeks and 24 weeks [p < 0.05 (*)] of duration of diabetes when compared with their respective controls (d) Diffuse damage density is significantly [(p < 0.01)] higher at 12 weeks of duration of diabetes compared to control.