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. 2019 Nov 18;9:16963. doi: 10.1038/s41598-019-53349-1

Table 6.

Post surgery patient score calculation and BRS.

BRS Patient score*
Negative <0.200
Positive ≥0.200

*Patient Score = 7.322 + 1.773 *log(H-FABP) + 1.120 *log(MK) + 3.510 *log(sTNFR2).

The patient score equation was derived from logistic regression. The cut-off (0.200) was manually determined to optimise sensitivity while maintaining specificity. If the patient score was < 0.200 then BRS is negative for AKI, if the patient score ≥ 0.200 then BRS is positive for AKI.

BRS, biomarker risk score; H-FABP, heart-type fatty acid-binding protein; MK, midkine; sTNFR2, soluble tumour necrosis factor receptor 2; AKI, acute kidney injury.