Table 6.
BRS | Patient score* |
---|---|
Negative | <0.200 |
Positive | ≥0.200 |
*Patient Score = 7.322 + 1.773 *log(H-FABP) + 1.120 *log(MK) + 3.510 *log(sTNFR2).
The patient score equation was derived from logistic regression. The cut-off (0.200) was manually determined to optimise sensitivity while maintaining specificity. If the patient score was < 0.200 then BRS is negative for AKI, if the patient score ≥ 0.200 then BRS is positive for AKI.
BRS, biomarker risk score; H-FABP, heart-type fatty acid-binding protein; MK, midkine; sTNFR2, soluble tumour necrosis factor receptor 2; AKI, acute kidney injury.