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. 2019 Nov 18;9:16980. doi: 10.1038/s41598-019-53123-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Microarray of the pooled mRNA samples from haze predisposed and control groups reveals 292 upregulated and 567 downregulated genes cut off > ±2 fold change (p-value < 0.05). (a) Graph represents data of 859 genes differentially regulated. (b) STRING analysis of gene networks and pathways differentially regulated in haze predisposed and post PRK haze groups of patients. 38 differentially expressed genes (triangle shapes, red color signifies up regulation and green down regulation respectively) related to 21 molecular functions (green circles) were observed to be associated with 7 important pathways (square box).