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. 2019 Nov 12;10:1111. doi: 10.3389/fgene.2019.01111

Figure 5.

Figure 5

Cell motility changed significantly following ZFAS1 overexpression and knockdown. (A) SK-Hep1 cells transfected with ZFAS1 expression plasmid. The cell motility of SK-Hep1 cells was significantly increased following transfection with the ZFAS1 expression plasmid (p-value = 9e−04, paired Student’s t-test, n = 3). (B) SK-Hep1 cells transfected with small interfering RNAs (siRNAs) of ZFAS1. The cell motility of SK-Hep1 cells decreased significantly following transfection with the two independent siRNAs (siGFP vs. siZFAS1-1: P-value = 7e−04, siGFP vs. siZFAS1-2: P-value = 3.2e−03, paired Student’s t-test, n = 3). Imax means cells exposed to Lipofectamine RNAiMAX but not RNA duplexes. siGFP indicates cells transfected with siRNA of green fluorescent protein. **P-value < 0.01, ***P-value < 0.001.