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. 2019 Nov 12;10:1111. doi: 10.3389/fgene.2019.01111

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Copyright © 2019 Guo, Meng, Zhai, Xie, Zhao, Li, Zhou, Li, Liu, Yang and Wu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Change in reactive oxygen species (ROS) production following ZFAS1 knockdown. Cellular ROS production was significantly downregulated following transfection of SK-Hep1 cells with two independent siRNAs (siGFP vs. siZFAS1-1: P-value = 0.022, siGFP vs. siZFAS1-2: P-value = 0.025, paired Student’s t-test, n = 3). Imax means cells exposed to Lipofectamine RNAiMAX but not RNA duplexes. siGFP indicates cells transfected with small interfering RNAs of green fluorescent protein. *P-value < 0.05.