Figure 11.

Results of the force dependencies of velocity and run length for dimerized kinesin-3 with reduced affinity E_w2 at saturating ATP. The theoretical data are calculated with E_NL = 5k_BT and other parameter values given in Table 1 for kinesin-3 and n = 10 except for E_w2 = 40.5k_BT. The experimental data are taken from Tomishige et al.²². (a) Calculated run length distribution under no load. (b) Experimentally measured run length distribution under no load for U356-Kstalk-GFP-K0. (c) Calculated dissociation rate versus load (unfilled circles). λ = 5. (d) Experimentally measured dissociation rate versus load for U356-Kstalk-GFP-K0 (unfilled circles). The filled circles in (c) are calculated data with E_w2 ≥ 45k_BT and λ = 5. The filled circles in (d) are experimental data for U356-Kstalk-GFP.