Figure 2.
Efficacy of combination treatments. (A) Scheme of different treatments, triangles indicate days of treatment; (B,C) Kaplan–Meier representation of two independent experiments. Survival was calculated as the fraction of living animals with tumor size <1,500 mm3; (B) mock treated (n = 6, black), treated with carboplatin (n = 8, small dotted black), AsiDNA (n = 8, gray), or combination of AsiDNA and carboplatin (n = 10, large dotted black); (C) mock treated (n = 6, black), treated with carboplatin (n = 6, small dotted black), olaparib (n = 9, gray), or combination of olaparib and carboplatin (n = 10, large dotted black).