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. 2019 Nov 12;9:1196. doi: 10.3389/fonc.2019.01196

Figure 4.

Figure 4

Tumor metastasis prevention effects via IR-780 induced long-term immune memory. (A) Therapeutic schedule for IR-780 mediated inhibition of tumor metastasis in mouse model. (B) Representative photographs of lung tissue in different group mice. (C) Quantification of pulmonary metastasis nodules on control mice or mice pre-vaccinated with IR-780 treated CT26 cancer cells. (D) H&E staining of the lung tissue collected at day 20; Scale bars = 200 μm. (E, F) Quantification of pulmonary metastasis neoplasia and tumor sizes on pulmonary sections. (G) The proportions of effector memory T cells (CD8+CD44+CD62L−) in the spleen of different group mice detected by flow cytometry. All the data are presented as mean ± SD. **p < 0.01.