Table 1.

Treatment dosing, administration, and drug acquisition costs^a

	Fulvestrant (first 4 weeks)	Fulvestrant (after first 4 weeks)	Anastrozole	Letrozole	Tamoxifen
Label information
Administration method	Intravenous	Intravenous	Oral	Oral	Oral
Dose per administration (mg)	500	500	1	2.5	20
Administration frequency	2 per 4 weeks	1 per 4 weeks	1 per day	1 per day	1 per day
Package information
Formulation (mg)	250	250	1	2.5	20
Pack size	2	2	28	28	30
Cost per pack (£)	522.41	522.41	0.75	1.52	1.62

^aDosing information sourced from British National Formulary labels [44], acquisition costs (British pounds sterling; 2016) sourced from the National Health Service drugs and pharmaceutical electronic market information tool [45]