Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 12;7:267. doi: 10.3389/fcell.2019.00267

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Wu, Tang, Yin, Yan, Tang, Xin, Pan, Ma and Yan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Schematic diagram of the potential effect of the RT and AT-MSCs combination therapy on HCC. Our results suggest that the synergistic treatment effect of RT and AT-MSCs has therapeutic potential for HCC in mice via the inhibition of IFITM1 expression, inhibition of HCC cell proliferation via upregulation of p53 and p21, inhibition of tumor invasion via downregulation of MMPs, and promotion of HCC cell apoptosis. AT-MSCs: adipose tissue-derived mesenchymal stem cells; AT-CM: conditioned medium (CM) from AT-MSCs; IFITM1: interferon-induced transmembrane protein 1; STAT3: signal transducer and activator of transcription 3; MMP: matrix metallopeptidases.