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. 2019 Nov 12;10:1189. doi: 10.3389/fneur.2019.01189

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Copyright © 2019 Wang, Zhang, Yu, Shen, Wu and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cognitive performance after enriched environment (EE) intervention in the acquisition trial and probe test of Morris water maze (MWM). (A) Escape latency. Data are expressed as mean ± SEM, n = 8 per group. *P < 0.05, EE vs. the standard housing (SH) group. (B) Track plots showed the trace of mice in the tank during the probe test. (C) Total distance traveled in the four water maze zones. (D) Distance traveled in the correct (NE zone) quadrant. (E) Time spent in the correct quadrant (NE zone). (F) Number of crossings of the previous platform. Data are expressed as mean ± SEM, n = 8 per group. *P < 0.05, the EE group vs. the SH group.