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. 2019 Nov 12;10:1189. doi: 10.3389/fneur.2019.01189

Figure 5.

Figure 5

Enriched environment (EE) improved the expression of ipsilateral and contralateral GAP after permanent middle cerebral artery occlusion (pMCAO). (A) Representative immunofluorescence images of hippocampus CA3 of the ipsilateral and contralateral GAP (red) in the sham, standard housing (SH), and EE groups. Scale bar = 100 μm. (B) Bar graph shows the immunofluorescence quantification of the expression of ipsilateral and contralateral GAP-43 among different groups. (C) Representative Western blot images of the ipsilateral and contralateral GAP-43 in the sham, SH, and EE group. (D) Bar graph shows the Western blot quantification of the expression of ipsilateral and contralateral SYN among different groups. Data are expressed as mean ± SEM, n = 8 per group. *P < 0.05, the EE group vs. the SH group in the ipsilateral. #P < 0.05, the SH group vs. the sham group in the ipsilateral. **P < 0.05, the EE group vs. the SH group in the contralateral. ##P < 0.05, the SH group vs. the sham group in the contralateral.