Table I.
Criteria for staging and grading chronic hepatitis (2000, Xi’an).
| Inflammatory activity | Degree of fibrosis | |||
|---|---|---|---|---|
| Grade | Portal area and periphery | Intralobular | Stage | Fibrosis |
| G0 | No inflammation | No inflammation | S0 | None |
| G1 | Portal area inflammation | Degeneration and a little focal necrosis | S1 | Portal area expansion, fibrosis |
| G2 | Mild piecemeal necrosis | Degeneration, spotted and focal necrosis or acidophilic body | S2 | Fibrous septum is forming, and lobular structure is retained |
| G3 | Moderate piecemeal necrosis | Degeneration, severe necrosis or visible bridging necrosis | S3 | Fiber insulation with lobular disorder, without liver cirrhosis |
| G4 | Severe piecemeal necrosis | Wide area of bridging necrosis to involve multiple lobules, lobular structure disorder | S4 | Forepart hepatocirrhosis |