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. 2019 Nov-Dec;35(6):1505–1510. doi: 10.12669/pjms.35.6.652

Table III.

Adverse effects and inadequate response reported with Gabapentinoids.

Adverse effects observed in patients who completed the study (n=252)

Drugs Adverse effects n (%) Mean dose ±SD (mg/d)
Pregabalin Dizziness, Drowsiness, Somnolence 58 (23) 95.43±53.06
Visual Blurring 3 (1.19) 125.00±90.14
Ataxia 4 (1.58) 56.25±10.83
Weight Gain 1 (0.39) 300
Gabapentin Dizziness, Drowsiness, Somnolence 10 (3.96) 360±171.27

Patients’ non-compliance due to severe adverse effects (n=28)

n (%) Mean dose ±SD (mg/d)
Pregabalin 15 (54) 112.00±48.17
Gabapentin 13 (46) 375.68±189.70

Patients with inadequate response (n=24)

Pregabalin 7 (29) 126.21±49.20
Gabapentin 17 (71) 325.58±162.73

Lost to follow up (n=16)

Pregabalin 4 (25) 106.28±80.24
Gabapentin 12 (75) 384.38±177.64