Table II.

HNSCC characteristics.

Parameter	Addicted patient (n = 185)	Non-addicted patient (n = 26)
	No. (%)	No. (%)	χ2 value	p-value
HNSCC site			30.0	< 0.001
Oral cavity	157 (84.9)	15 (57.7)	12.5	0.132
Buccal mucosa	103 (65.6)	5 (33.3)
Tongue	30 (19.1)	5 (33.3)
Lip	7 (4.4)	0 (0.0)
Gingival	5 (3.2)	2 (13.3)
Palate	4 (2.5)	1 (6.7)
Alveolar ridge	3 (1.9)	1 (6.7)
Retromolar trigone	2 (1.3)	0 (0.0)
Floor of mouth	1 (0.6)	0 (0.0)
Buccal mucosa with any other subsite of oral cavity	2 (1.3)	1 (6.7)
Larynx	14 (7.6)	1 (3.8)	1.22	0.747
Glottis	6 (42.9)	1 (100.0)
Supraglottis	4 (28.6)	0 (0.0)
Laryngeal wall	3 (21.4)	0 (0.0)
Vocal cords	1 (7.1)	0 (0.0)
Hypopharynx	6 (3.2)	3 (11.5)	6.00	0.112
Pyriform sinus	4 (66.7)	0 (0.0)
Hypopharyngeal wall	1 (16.7)	2 (66.7)
Cervical	1 (16.7)	0 (0.0)
Post cricoid	0 (0.0)	1 (33.3)
Oropharynx	2 (1.1)	0 (0.0)
Tonsil	1 (50.0)	0 (0.0)
Oropharyngeal wall	1 (50.0)	0 (0.0)
Nasal cavity	1 (0.5)	1 (3.8)	2.00	0.157
Lateral wall	1 (100.0)	0 (0.0)
Floor	0 (0.0)	1 (100.0)
Eye	2 (1.1)	2 (7.7)	0.00	1.000
Orbit	1 (50.0)	1 (50.0)
Eyelid	1 (50.0)	1 (50.0)
Ear	2 (1.1)	1 (3.8)	2.00	0.157
Middle ear	2 (100.0)	0 (0.0)
Auricle	0 (0.0)	1 (100.0)
Nasopharynx	1 (0.5)	3 (11.5)
Differentiationa			9.10	0.011
Well	52 (30.5)	1 (4.3)
Moderate	111 (65.3)	19 (82.6)
Poor	7 (4.1)	3 (13.0)
Stageb			5.21	0.391
0	3 (3.1)	0 (0.0)
I	1 (1.0)	0 (0.0)
II	13 (13.3)	3 (30.0)
III	36 (36.7)	5 (50.0)
IV A	40 (40.8)	1 (10.0)
IV B	5 (5.1)	1 (10.0)

^aDifferentiation was not recorded for 15 addict and 3 nonaddict patients,

^bStage was not recorded for 87 addict and 16 non-addict patients.