Table I.
Association of miR-196a genotype and allelic frequencies in cases and Controls.
| SNP 196 C>T | Cases N=295 | Controls N=295 | OR (95% CI) | p - Value |
|---|---|---|---|---|
| Genotype | n(%) | n(%) | ||
| CC | 240 (81.4) | 218 (73.9) | Ref 1 | |
| CT | 47 (15.9) | 49 (16.6) | 0.87 (0.56-1.35) | 0.53 |
| TT | 8 (2.7) | 28 (9.5) | 0.25 (0.11-0.58) | 0.00 |
| Dominant Model | ||||
| CC | 240 (81.4) | 218 (73.9) | -- | |
| TT+CT | 55 (18.6) | 77 (26.1) | 0.64 (0.43-0.95) | 0.02 |
| Recessive Model | ||||
| CC+CT | 287 (97.2) | 267 (90.5) | -- | |
| TT | 8 (2.7) | 28 (9.5) | 0.26 (0.11-0.59) | 0.00 |
| Alleles | ||||
| C | 527 (89.3) | 485 (82.2) | -- | |
| T | 63 (10.6) | 105 (17.7) | 0.55 (0.39-0.77) | 0.00 |
OR – Odds Ratio, CI- confidence Interval, P <0.05 – statistically significant.