FIGURE 4.

Changes in pubertal hormone levels according to Tanner stage and approximate age (mean ± standard error). Hormone concentrations for luteinizing hormone (LH) (Burger et al., 1988). follicle stimulating hormone (FSH) (Burger et al., 1988), Estradiol (E2) (Wennink et al., 1990), progesterone (Apter, 1980), inhibins (Wennink et al., 1990), growth hormone (GH) (Rose et al., 1991), insulin-like growth factor-1 (IGF-1) (Moran et al., 2002), insulin (Moran et al., 2002), triiodothyronine (T3) (Elmlinger et al., 2001), thyroxine (T4) (Elmlinger et al., 2001), cortisol (Stroud et al., 2011), leptin (Ahmed et al., 1999), melatonin (Crowley et al., 2012) are shown through the Tanner stages for females. Note that standard errors were not available for estradiol or melatonin data. Standard errors for LH, FSH and inhibins were approximated based on data provided. Cyclical changes in hormone levels with menstruation are not reflected.