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. 2019 Nov 12;24:102088. doi: 10.1016/j.nicl.2019.102088

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© 2019 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig 2: — The group differences of FC. (A) The regions displayed significant difference among the three groups (Thalamus & Medial Frontal Gyrus). The result was corrected by Monte Carlo simulation with settings of voxel-wise P<0.01, FWHM = 6 mm, and cluster size>1215mm³. The scale was made up of correlation coefficients between PCC and brain regions within DMN and the 11 value in scale expressed the max correlation coefficients. (B) Subjects in the WMH III group displayed significantly greater FC in MFG than the other two groups. (C) Subjects in the WMH III group displayed significantly lower FC in thalamus than the other two groups. * P<0.05. Abbreviations: FC, functional connectivity; WMH, white matter hyperintensities; PCC, posterior cingulate cortex; DMN, default mode network; MFG, medial frontal gyrus.