Correlation analyses between cognitive function and FC in the WMH III group. (A) FC of PCC- MFG was negatively correlated with episodic memory [r ==−0.467, P = 0.029; 95% CI (−0.796, −0.034) ]. (B) FC of PCC-thalamus was positively correlated with language [r = 0.502, P = 0.017; 95% CI (0.084, 0.763)]. (C) FC of PCC-thalamus was negatively correlated with the time of processing speed [r ==−0.528, P = 0.012; 95% CI (−0.800, −0.167)]. (D) FC of PCC-thalamus was negatively correlated with the time of executive function [r ==−0.504, P = 0.017; 95% CI (−0.802, −0.178)]. The scores of each domain were z-transformed scores of the relevant tests. Correlation analyses were performed after adjustment of covariates (sex, age, and years of education). Abbreviations: FC, functional connectivity; WMH, white matter hyperintensities; PCC, posterior cingulate cortex; MFG, medial frontal gyrus; CI, confidence interval.