Comparison of FA or MD values across three groups. (A) The mean FA value of the PCC-hippocampus in the WMH III group was the lowest among the groups, even though it has not reached statistical significance. (B) The mean MD value of the PCC-hippocampus in the WMH III group was significantly higher than the former two groups. (C) The mean FA value of the PCC-thalamus was significantly lower than the former two groups. (D) The mean MD value of the PCC-thalamus was significantly higher than the former two groups. *: P<0.05. Abbreviations: FA, fractional anisotropy; MD, mean diffusivity; PCC, posterior cingulate cortex; WMH, white matter hyperintensities.