Table 1.
Demographic and neuroimaging characteristics.
| Items | WMH I | WMH II | WMH III | p-value |
|---|---|---|---|---|
| Age | 58.00(11.00) | 66.35±7.26a | 70.24±5.47a | <0.001* |
| Edu | 12.00(7.00) | 12.00(6.00) | 11.24±3.69 | 0.120 |
| Gender (male:female%) | 32:25(56.0:44.0) | 19:15(55.9:44.1) | 11:14(44.0:56.0) | 0.564 |
| Hypertension (yes:no%) | 25:32(44.0:56.0) | 24:10(70.6:29.4) | 22:3(88.0:12.0) | <0.001* |
| Diabetes (yes:no%) | 7:50(12.3:87.7) | 8:26(23.5:76.5) | 3:22(12.0:88.0) | 0.308 |
| Smoking history (yes:no%) | 10:47(17.5:82.5) | 4:30(11.8:88.2) | 3:22(12.0:88.0) | 0.688 |
| Drinking history (yes:no%) | 9:48(15.8:84.2) | 6:28(17.6:82.4) | 4:21(16.0:84.0) | 0.972 |
| WMH volume(ml) | 469.70±214.64 | 1869.90(772.09)a | 6614.89(8824.82)a,b | <0.001* |
| lg WMH | 2.70(0.33) | 3.27±0.13a | 3.88±0.30a,b | <0.001* |
| lacune | 0.00 (1.00) | 0.00 (1.00) | 1.00 (1.00) | 0.062 |
| CMB | 0 | 0 | 0 | / |
Note: Values with normal distribution are presented as the mean ± stand deviation (SD); Values with non-normal distribution are presented as median(interquartile). χ2 test was applied in the comparisons of gender, hypertension, diabetes and smoking history; nonparametric test was applied in the other comparisons. *: p<0.05; a: p<0.05 differ from WMH I; b: p<0.05 differ from WMH II. Abbreviations: WMH, white matter hyperintensity; CMB, cerebral microbleeds.