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. 2019 Oct 18;18:774–786. doi: 10.1016/j.omtn.2019.10.009

Figure 1.

Figure 1

Size and ζ-potential of Polyplexes Evaluated by NTA

(A and B) Hydrodynamic diameter (A) and changes in the percentage of particles below 200 nm (B) of polyplexes prepared at pDNA concentrations of 20 or 267 μg/mL at N/P 9 in HBG. (C) ζ-Potential of polyplexes generated with 267 μg/mL pDNA at N/P 9 (n = 3 + SD). (D–F) Representative particle size distribution of polyplexes based on LPEI (D), LPEI-PEG (E), and LPEI-PEG-CD49f (F) at pDNA concentration of 267 μg/mL and N/P 9 before and after aerosolization by microspraying (MS).