Table 1.
Analogue | ChemPLP (with DNA) | ChemPLP (no DNA) | Strand transfer activity IC50 (μM)a |
---|---|---|---|
1 | 58.01 | 38.29 | 1.3 |
2 | 36.08 | 26.93 | >1600 |
3 | 42.44 | 40.32 | 14 |
4 | 56.35 | 41.98 | 19 |
5 | 31.73 | 28.20 | 22 |
6 | 33.43 | 43.44 | 49 |
7 | 38.50 | 29.69 | 24 |
8 | 37.22 | 24.88 | 25 |
Activities from references [10] and [11].