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. 2019 Nov 7;17:1348–1359. doi: 10.1016/j.csbj.2019.10.004

Table 2.

A comparison of targeted methods of genomic analysis.

Platform Target size Cost (per sample, USD) Massively Parallel Minimum allele frequency Purpose in Research
TS ~1 × 105–1 × 107 bp $300–$1000 True 1% (without error suppression) Discovery/Validation
Sanger Sequencing 300–1000 bp <$30 False ~15% Validation
Digital PCR 1–80 bp <$10 False <0.001% Validation