Table 3.
Demographic characteristics, clinical data, injury scores and laboratory parameters at hospital admission, by study period, among propensity-score matched patients.
| Propensity-score matched cohort (n = 183) |
|||
|---|---|---|---|
| Pre ECS (n = 92) | ECS (n = 91) | p-valuea | |
| Inclusion criteria, n (25th, 75th percentiles) | 1 (1, 2) | 1 (1, 2) | 0.9 |
| Mean age, years (SD) | 49.4 (21) | 48.3 (19.6) | 0.7 |
| Men, n (%) | 65 (70.7%) | 71 (78%) | 0.3 |
| Mean SBP, mmHg (SD) | 97.6 (31.5) | 95.6 (33) | 0.7 |
| Median GCS (25th, 75th percentiles) | 13 (7, 15) | 14 (8, 15) | 0.3 |
| Median ISS (25th, 75th percentiles) | 34 (24.5, 41) | 32 (19, 42) | 0.4 |
| AIS head ≥ 4, n (%) | 26 (28.3%) | 25 (27.5%) | 0.9 |
| AIS chest ≥ 4, n (%) | 39 (42.4%) | 36 (39.6%) | 0.7 |
| AIS abdomen ≥ 4, n (%) | 32 (34.8%) | 21 (23.1%) | 0.1 |
| AIS pelvis and limbs ≥ 4, n (%) | 18 (19.6%) | 31 (34.1%) | 0.03 |
| AIS face ≥ 4, n (%) | 13 (14.1%) | 7 (7.7%) | 0.2 |
| AIS extremities ≥ 4, n (%) | 4 (4.3%) | 6 (6.6%) | 0.5 |
| Mean pH (SD) | 7.3 (0.1) | 7.3 (0.1) | 0.2 |
| Mean lactate, mmol/L (SD) | 4.1 (2.3) | 3.8 (2.8) | 0.5 |
| Mean BE, mmol/L (SD) | −6.8 (3.6) | −7 (3.6) | 0.7 |
| Mean fibrinogen, mg/dL (SD) | 207.5 (89.9) | 203.7 (108.9) | 0.8 |
| Mean INR (SD) | 1.2 (0.3) | 1.3 (0.4) | 0.6 |
| Mean haemoglobin, g/d (SD) | 11.4 (2.6) | 11.1 (2.6) | 0.4 |
| Mean PLT, x1000/dL (SD) | 211 (83.4) | 192.9 (75.4) | 0.1 |
AIS = anatomical injury score; BE = base excess; GCS = Glasgow coma score; INR = international normalized ratio; ISS = injury severity score; PLT = platelets; SBP = systolic blood pressure.
a
p-value for testing the null hypothesis of no difference in the patients' characteristics between the two study periods. Test statistic: chi-square, t-test and Wilcoxon rank test for dichotomic, continuous and discrete variables, respectively.