Specifications Table

Subject	Critical Care and Intensive Care Medicine
Specific subject area	Haemostasis/coagulopathy
Type of data	Tables Graph
How data were acquired	Data were retrospectively acquired from the registry data of the emergency department of two Italian trauma centres.
Data format	Raw and analysed
Parameters for data collection	Overall cohort: patients who were consecutively admitted with major trauma who had, or were at risk of, active bleeding, managed according to the massive transfusion (2011–2012) or the early coagulation protocol (2013–2014). Study cohort: patients who, according to international guidelines, was considered at risk of requiring multiple transfusions.
Description of data collection	Data from all major trauma patients with ISS >15 who were admitted to the ICU were included into Trauma Centre's databases (overall cohort). Data from patients who met the inclusion criteria were included into the multicentre database (study cohort). These data were matched with blood bank registries and the amounts of packed red blood cells, fresh frozen plasma, and platelet units administered within 24-h after admission were recorded.
Data source location	Fondazione Policlinico Universitario Agostino Gemelli IRCCS (Rome, Italy) Azienda Ospedaliera San Camillo Forlanini (Rome, Italy)
Data accessibility	With the article (Supplementary material)
Related research article	Maria Grazia Bocci et al. Early coagulation support protocol: a valid approach in real-life management of major trauma patients. Results from two Italian centres. Injury (In Press)