Scatter plots of the automated segmentation lesion volumes versus manual lesion volumes obtained from LesionTOADS (green), LST-LPA default (blue), LST-LPA adjusted-threshold (turquoise), nicMSlesions default (pink), nicMSlesions optimized (purple), and BIANCA (yellow). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)