Table 2. Trauma patient population demographics, hematology and clinical outcomes.
Numbers presented as median with 25 and 75 interquartile range or raw number with percent total as appropriate.
| Demographics | |
| Age (y) | 33.5 (25.5-46.6) |
| % male | 44 (76%) |
| Injury Characteristics | |
| % blunt mechanism | 32 (55%) |
| Time from injury to arrival (min) | 27 (21-34) |
| NISS | 17 (9-34) |
| % TBI | 18 (31%) |
| Laboratory Values | |
| SBP (mm Hg) | 119 (92-136) |
| Lactate (mmol/L) | 3.5 (2.2-6.6) |
| Base deficit (meq/L) | 5.8 (3.4-10.6) |
| PT/INR | 1.1 (1.0-1.2) |
| PTT (s) | 25.8 (23.3-27.9) |
| Thrombelastography | |
| ACT (seconds) | 105 (97-121) |
| Angle (degrees) | 74.4 (67.6-77.8) |
| MA (mm) | 62.0 (57.5-65.0) |
| LY30 (%) | 1.6 (0.5-3.0) |
| Whole Blood Thrombin Generation | |
| Lag time (min) | 3.8 (2.8-4.9) |
| Peak thrombin (nM) | 86.4-146.7) |
| Time to peak thrombin (min) | 6.7 (4.9-9.1) |
| Maximum rate (nM/min) | 42.6 (22.9-61.6) |
| ETP (nM.min) | 823 (711-966) |
| Clinical Outcomes | |
| RBCs/1st 6 h (units) | 0 (0-2) |
| % massive transfusion (>10 units RBCs/1st 6 ) | 3 (5%) |
| ICU LOS (days) | 3 (0-5) |
| Ventilator days | 1 (0-3) |
| Hospital duration of stay (days) | 4 (3-13) |
| % mortality | 10 (17%) |
NISS=new injury severity score, TBI=traumatic brain injury (defined as head and neck abbreviated injury score ≥ 3), SBP=systolic blood pressure, PT/INR=prothrombin time/international normalized ratio, PTT=activated partial prothrombin time, ACT=activating clotting time, MA=maximum amplitude, LY30=fibrinolysis 30 minutes after MA, ETP=endogenous thrombin potential, RBC=red blood cells, ICU=intensive care unit,