Table 2.
Disconnectivity changes over time for each resting-state network.
| Nn˚ | Effect REGION[F p η] | Least disconnected ROI (ds) | Most disconnected ROI (ds) | Effects TIME [F p η] | Effects TIME + ΔDO80 [F p η] | Post-hoc WSRT, effect of timep < 0.05 | |
|---|---|---|---|---|---|---|---|
| dDMN | 9 | 44.20, 0.00, 0.65 | Angular R (0.018) | Thalamus L (0.676) | X | x | X |
| vDMN | 10 | 20.98, 0.00, 0.43 | Angular R (0.063) | Parahippocamp L (0.451) | Main [5.46, 0.00, 0.16] | x | General decrease, Especially for parahippocamp R |
| Language | 7 | 23.45, 0.00, 0.51 | Frontal inf R (0.094) | Temporal mid L (0.420) | Interact [3.52, 0.02, 0.13] | Interact [3.01, 0.04, 0.14] | Increase: Supramarginal, temporal mid/sup L Decrease: cereb crus I L. |
| LECN | 6 | 30.06, 0.00, 0.49 | Parietal inf/angul L (0.198) | Thalamus L (0.721) | Interact [3.09, 0.03, 0.09] | x | Decrease: cereb crus I R, front mid/sup L |
| RECN | 6 | 18.52, 0.00, 0.43 | Parietal inf/angul R (0.047) | Caudate R (0.517) | Interact [3.19, 0.03, 0.11] | X | Decrease: cereb crus I/II L + vermis, caudate R, front mid/sup R |
| Salience | 7 | 7.569, 0.00, 0.22 | Insula R (0.088) | Cingulate ant (0.337) | x | X | x |
| Post-Salience | 12 | 93.99, 0.00, 0.81 | Supramarginal R (0.045) | Thalamus L (0.846) | Main [12.29, 0.00, 0.33] Interact [3.73, 0.01, 0.13] |
Main [8.25, 0.01, 0.28] | General decrease, especially for cereb VI L, thalamus R |
| Visuo-spatial | 11 | 15.59, 0.00, 0.42 | Temporal inf/mid R (0.041) | Frontal inf/oper L (0.343) | x | x | x |
| High-visual | 2 | 42.87, 0.00, 0.57 | Occipital mid/sup R (0.066) | Occip mid/sup L (0.196) | x | x | x |
| Primary visual | 1 | x | Calcerine/occip inf RL (0.117) | x | Main [6.85, 0.01, 0.18] | Main [5.54, 0.03, 0.17] | General decrease, especially for Thalamus L |
| Basal ganglia | 5 | 24.33, 0.00, 0.54 | Frontal inf R (0.294) | Thalamus L (0.869) | x | x | x |
| Precuneus | 4 | 88.28, 0.00, 0.76 | Angular R (0.038) | Cingul mid/post RL (0.445) | x | x | x |
| Sensori-motor | 6 | 64.72, 0.00, 0.68 | Central pre/post R (0.117) | Thalamus L (0.837) | Main [9.76, 0.00, 0.25] | Main [6.73, 0.02, 0.21] | Decrease: Cereb IV-VI + vermis B, thalamus B, SM1 B, SMA B. |
| Auditory | 3 | 51.69, 0.00, 0.70 | Temporal sup R (0.063) | Thalamus R (0.532) | Main [11.72, 0.00, 0.27] Interact [6.25, 0.01, 0.17] |
Main [7.16, 0.01, 0.21] | General decrease, especially for thalamus R |
Nn = number of regions within network, ROI = region of interest, ds = disconnectome score. η = partial eta squared. +ΔDO80 = change in score on the DO80 picture naming task, added as a covariate to the ANOVA, WSRT = post-hoc Wilcoxon Signed Rank Test pre-post surgery.