Table 2.
Summary of the changes in clinical biomarkers and well-being during fasting
(Mean values, ranges and standard deviations)
| Parameter | Pre-fasting | End of fasting | 3 d after | After 3 months | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | Range | sd | Mean | Range | sd | P | Mean | Range | sd | P | Mean | Range | sd | P | |
| Weight (kg) | 85·7 | 70·5–106·9 | 1·0 | 79·8 | 66·1–99·5 | 9·6 | *** | 79·7 | 66·5–100·1 | 9·5 | *** | 81·9 | 70·4–99·5 | 8·3 | NS |
| BMI (kg/m2) | 26·5 | 20·4–32·3 | 3·0 | 24·7 | 19·2–30·0 | 2·7 | *** | 24·7 | 19·4–30·1 | 2·7 | *** | 25·5 | 21·1–31·8 | 2·6 | * |
| SBP (mmHg) | 128·3 | 96–158 | 14·6 | 121·1 | 104–152 | 11·3 | * | 116·1 | 103–140 | 9·6 | *** | 127·6 | 104–142 | 10·2 | NS |
| DBP (mmHg) | 81·6 | 57–90 | 9·3 | 77·7 | 64–87 | 6·5 | * | 77·6 | 66–100 | 9·0 | * | 81·2 | 72–95 | 7·2 | NS |
| Waist (cm) | 92·7 | 76–108 | 9·1 | 89·0 | 74–106 | 9·0 | ** | 89·7 | 80–104 | 7·5 | ** | 92·1 | 80–108 | 7·1 | NS |
| Emotional well-being, score 0–10 | 7·3 | 4–10 | 1·9 | 8·3 | 2–10 | 2·1 | NS | 9·1 | 6–10 | 1·2 | *** | 7·9 | 4–10 | 1·6 | NS |
| Physical well-being, score 0–10 | 6·8 | 3–10 | 2·4 | 7·8 | 1–10 | 2·4 | NS | 9·0 | 5–10 | 1·5 | *** | 8 | 5–10 | 1·4 | * |
SBP, systolic blood pressure; DBP, diastolic blood pressure.
Significantly different at end of fasting in comparison with pre-fasting baseline levels: *P < 0·05, **P < 0·01, ***P < 0·001 (ANOVA).