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. 2019 Oct;7(20):540. doi: 10.21037/atm.2019.10.16

Figure 3.

Figure 3

Knockdown of HSPA2 induced G1/S phase cell cycle arrest. (A) HSPA2 knockdown induced the G1/S phase cell cycle arrest of A549 and H1975 cells. Cell cycle profiles of A549 and H1975 cells transfected with HSPA2 siRNA and control cells were determined by flow cytometry and error bars. Cell count versus PI staining is shown (10,000 per treatment). (B) HSPA2 knockdown induced the change of G1/S phase regulation and checkpoint proteins of A549 and H1975 cells. Western blot analysis of G1/S phase cell cycle regulation and checkpoint proteins with A549 and H1975 cell transfected with HSPA2 siRNA and control cells are shown. *, P<0.05.