Moxibustion preconditioning attenuated MIRI-induced pathological morphological changes in the ventricular tissues (n=3 each group) and reduced MIRI-induced myocardial enzyme levels (n=9 each group). (A) The arrows indicate areas of inflammatory cell infiltration (HE, ×400); (B,C) levels of cTnT and LDH in the serum of rats with sham operation (Sham), myocardial ischemia reperfusion (MIR), moxibustion pretreatment plus MIRI (Moxi), and autophagy inhibitor plus MIRI (3-MA). All data are expressed as mean ± SD. **, P<0.01 vs. Sham group; ##, P<0.01 vs. MIR group. MIRI, myocardial ischemia reperfusion injury; LDH, lactate dehydrogenase.