Table S1. Details of the seven risk scores of splicing events.
| Type | ID | Exp (coef) | Lower | Upper | Se (coef) | Z score | Pr (>|z|) |
|---|---|---|---|---|---|---|---|
| All | COMT.61100.AT | 5.98E+12 | 2.45E+07 | 1.46E+18 | 6.33E+00 | 4.65E+00 | 3.36E-06 |
| PDHX.14973.ES | 5.33E-05 | 4.68E-07 | 6.07E-03 | 2.42E+00 | 4.07E+00 | 4.64E-05 | |
| RGS3.87287.AP | 1.38E-03 | 5.70E-05 | 3.34E-02 | 1.63E+00 | 4.05E+00 | 5.13E-05 | |
| NARF.44392.AP | 1.90E+04 | 3.57E+02 | 1.01E+06 | 2.03E+00 | 4.86E+00 | 1.18E-06 | |
| TSPAN14.12377.ES | 1.37E+02 | 1.48E+01 | 1.27E+03 | 1.14E+00 | 4.33E+00 | 1.50E-05 | |
| RPRD1B.59373.ES | 7.75E+02 | 3.49E+01 | 1.72E+04 | 1.58E+00 | 4.21E+00 | 2.60E-05 | |
| SPRYD7.25916.ES | 6.82E-03 | 6.91E-04 | 6.73E-02 | 1.17E+00 | 4.27E+00 | 1.95E-05 | |
| ABHD14B.65146.AA | 9.04E+01 | 9.64E+00 | 8.48E+02 | 1.14E+00 | 3.94E+00 | 8.03E-05 | |
| ADCY1.79596.AT | 1.48E+01 | 4.31E+00 | 5.09E+01 | 6.30E-01 | 4.28E+00 | 1.90E-05 | |
| PTGER3.3415.AT | 2.06E-02 | 3.08E-03 | 1.38E-01 | 9.70E-01 | 4.00E+00 | 6.28E-05 | |
| RBMS3.63800.AT | 3.18E+25 | 5.67E+12 | 1.78E+38 | 1.50E+01 | 3.92E+00 | 8.83E-05 | |
| CTNNAL1.87156.ES | 1.09E-34 | 1.53E-49 | 7.84E-20 | 1.75E+01 | 4.48E+00 | 7.44E-06 | |
| ZC3H14.28724.ES | 1.72E+01 | 4.81E+00 | 6.18E+01 | 6.52E-01 | 4.37E+00 | 1.25E-05 | |
| NUP160.15807.ES | 1.87E-05 | 8.30E-08 | 4.20E-03 | 2.76E+00 | 3.94E+00 | 8.14E-05 | |
| AA | DCAF4.28239.AA | 2.81E+02 | 3.60E+01 | 2.19E+03 | 1.05E+00 | 5.38E+00 | 7.64E-08 |
| DGKZ.15549.AA | 3.96E+10 | 1.63E+05 | 9.66E+15 | 6.33E+00 | 3.86E+00 | 1.15E-04 | |
| DPH5.3896.AA | 3.40E+05 | 3.52E+02 | 3.28E+08 | 3.51E+00 | 3.63E+00 | 2.81E-04 | |
| FKBP8.48446.AA | 6.87E-07 | 5.41E-10 | 8.71E-04 | 3.65E+00 | 3.89E+00 | 9.92E-05 | |
| LAIR1.51883.AA | 3.14E+01 | 6.40E+00 | 1.54E+02 | 8.11E-01 | 4.25E+00 | 2.15E-05 | |
| LTA4H.23825.AA | 3.79E-15 | 2.54E-21 | 5.67E-09 | 7.25E+00 | 4.58E+00 | 4.71E-06 | |
| PDDC1.13753.AA | 5.64E+03 | 1.02E+02 | 3.12E+05 | 2.05E+00 | 4.22E+00 | 2.46E-05 | |
| PKMYT1.33331.AA | 9.20E-03 | 7.13E-04 | 1.19E-01 | 1.30E+00 | 3.59E+00 | 3.27E-04 | |
| RALGAPB.59379.AA | 9.23E-03 | 8.86E-04 | 9.62E-02 | 1.20E+00 | 3.92E+00 | 8.91E-05 | |
| TREX1.64674.AA | 2.87E-02 | 5.79E-03 | 1.42E-01 | 8.16E-01 | 4.35E+00 | 1.34E-05 | |
| TYMP.62850.AA | 1.16E+01 | 2.86E+00 | 4.67E+01 | 7.13E-01 | 3.43E+00 | 5.95E-04 | |
| AD | ACAD9.66685.AD | 1.83E-02 | 1.80E-03 | 1.86E-01 | 1.18E+00 | 3.38E+00 | 7.28E-04 |
| ADAM15.7894.AD | 7.85E+00 | 2.02E+00 | 3.04E+01 | 6.92E-01 | 2.98E+00 | 2.89E-03 | |
| ALKBH6.49327.AD | 3.60E+03 | 5.61E+01 | 2.31E+05 | 2.12E+00 | 3.86E+00 | 1.15E-04 | |
| NUP98.13998.AD | 5.18E-02 | 8.85E-03 | 3.03E-01 | 9.01E-01 | 3.29E+00 | 1.01E-03 | |
| OXA1L.26618.AD | 6.32E+07 | 1.24E+04 | 3.21E+11 | 4.35E+00 | 4.13E+00 | 3.70E-05 | |
| PGD.612.AD | 1.56E-05 | 3.33E-08 | 7.31E-03 | 3.14E+00 | 3.53E+00 | 4.20E-04 | |
| PIGG.68359.AD | 8.25E-03 | 3.54E-04 | 1.93E-01 | 1.61E+00 | 2.98E+00 | 2.84E-03 | |
| AP | ABI2.57012.AP | 1.75E-15 | 2.18E-23 | 1.40E-07 | 9.29E+00 | 3.66E+00 | 2.53E-04 |
| COPS5.84054.AP | 2.10E-15 | 6.91E-24 | 6.40E-07 | 9.97E+00 | 3.39E+00 | 6.97E-04 | |
| LRP2BP.71337.AP | 1.15E-01 | 3.39E-02 | 3.92E-01 | 6.25E-01 | 3.46E+00 | 5.42E-04 | |
| AES.46658.AP | 1.78E+02 | 1.38E+01 | 2.31E+03 | 1.31E+00 | 3.97E+00 | 7.22E-05 | |
| NFIX.47899.AP | 3.54E+01 | 4.34E+00 | 2.89E+02 | 1.07E+00 | 3.33E+00 | 8.71E-04 | |
| WDR37.10611.AP | 9.93E+00 | 2.64E+00 | 3.73E+01 | 6.75E-01 | 3.40E+00 | 6.79E-04 | |
| C11orf68.16947.AP | 7.89E+01 | 9.84E+00 | 6.32E+02 | 1.06E+00 | 4.11E+00 | 3.90E-05 | |
| FAM228B.52812.AP | 1.34E+01 | 3.10E+00 | 5.80E+01 | 7.47E-01 | 3.48E+00 | 5.10E-04 | |
| MSANTD2.19240.AP | 1.58E+01 | 3.48E+00 | 7.20E+01 | 7.73E-01 | 3.57E+00 | 3.54E-04 | |
| TJAP1.76273.AP | 1.13E-03 | 2.92E-05 | 4.36E-02 | 1.86E+00 | 3.64E+00 | 2.73E-04 | |
| C11orf68.16948.AP | 1.53E-02 | 1.42E-03 | 1.65E-01 | 1.21E+00 | 3.44E+00 | 5.73E-04 | |
| CTNNBL1.59361.AP | 5.56E-17 | 1.49E-26 | 2.07E-07 | 1.12E+01 | 3.33E+00 | 8.73E-04 | |
| EPC1.11157.AP | 4.59E+01 | 5.26E+00 | 4.01E+02 | 1.11E+00 | 3.46E+00 | 5.39E-04 | |
| SLC29A1.76359.AP | 7.66E-02 | 2.51E-02 | 2.34E-01 | 5.70E-01 | 4.51E+00 | 6.57E-06 | |
| AT | C4orf29.70557.AT | 2.92E-03 | 9.28E-05 | 9.22E-02 | 1.76E+00 | 3.31E+00 | 9.19E-04 |
| LIMK2.61835.AT | 7.20E+01 | 6.38E+00 | 8.13E+02 | 1.24E+00 | 3.46E+00 | 5.45E-04 | |
| PTK2B.83154.AT | 6.51E+04 | 1.61E+02 | 2.63E+07 | 3.06E+00 | 3.62E+00 | 2.96E-04 | |
| DHRS12.25951.AT | 1.42E+03 | 2.80E+01 | 7.21E+04 | 2.00E+00 | 3.62E+00 | 2.92E-04 | |
| PTK2B.83155.AT | 2.44E-05 | 1.21E-07 | 4.93E-03 | 2.71E+00 | 3.92E+00 | 8.82E-05 | |
| TM2D1.3232.AT | 3.62E+04 | 7.14E+01 | 1.84E+07 | 3.18E+00 | 3.30E+00 | 9.58E-04 | |
| ACPP.66802.AT | 8.87E+00 | 2.73E+00 | 2.88E+01 | 6.02E-01 | 3.63E+00 | 2.86E-04 | |
| MAP3K8.11123.AT | 1.46E+01 | 3.11E+00 | 6.90E+01 | 7.91E-01 | 3.39E+00 | 6.91E-04 | |
| TMEM138.16187.AT | 5.16E+03 | 6.54E+01 | 4.07E+05 | 2.23E+00 | 3.84E+00 | 1.25E-04 | |
| FLCN.39460.AT | 6.79E+01 | 1.25E+01 | 3.70E+02 | 8.65E-01 | 4.87E+00 | 1.09E-06 | |
| HS2ST1.3691.AT | 2.66E+02 | 2.06E+01 | 3.44E+03 | 1.31E+00 | 4.28E+00 | 1.89E-05 | |
| FLCN.39461.AT | 3.33E-02 | 4.48E-03 | 2.48E-01 | 1.02E+00 | 3.32E+00 | 8.96E-04 | |
| HSPB7.787.AT | 1.06E+02 | 9.23E+00 | 1.21E+03 | 1.24E+00 | 3.75E+00 | 1.80E-04 | |
| HSPB7.788.AT | 4.21E-03 | 2.97E-04 | 5.96E-02 | 1.35E+00 | 4.04E+00 | 5.25E-05 | |
| HTRA3.68763.AT | 9.39E-03 | 7.09E-04 | 1.24E-01 | 1.32E+00 | 3.54E+00 | 4.00E-04 | |
| LRPAP1.68648.AT | 2.34E+08 | 2.80E+03 | 1.95E+13 | 5.78E+00 | 3.33E+00 | 8.60E-04 | |
| PTGER3.3415.AT | 3.25E-02 | 4.46E-03 | 2.38E-01 | 1.01E+00 | 3.38E+00 | 7.32E-04 | |
| ES | CFLAR.56797.ES | 5.47E-62 | 2.72E-87 | 1.10E-36 | 2.97E+01 | 4.75E+00 | 2.08E-06 |
| CTNND1.15999.ES | 2.27E-02 | 4.46E-03 | 1.16E-01 | 8.32E-01 | 4.55E+00 | 5.38E-06 | |
| MFAP5.20197.ES | 5.53E-02 | 1.41E-02 | 2.17E-01 | 6.98E-01 | 4.15E+00 | 3.37E-05 | |
| SMARCE1.40881.ES | 2.97E-55 | 1.18E-82 | 7.47E-28 | 3.22E+01 | 3.90E+00 | 9.61E-05 | |
| ZNF568.49434.ES | 4.53E-04 | 1.25E-05 | 1.64E-02 | 1.83E+00 | 4.21E+00 | 2.61E-05 | |
| C16orf13.32921.ES | 2.18E-02 | 4.15E-03 | 1.15E-01 | 8.47E-01 | 4.52E+00 | 6.20E-06 | |
| DUS2.37175.ES | 8.92E-06 | 3.32E-08 | 2.39E-03 | 2.85E+00 | 4.08E+00 | 4.60E-05 | |
| SUN2.62261.ES | 3.80E-07 | 8.39E-10 | 1.72E-04 | 3.12E+00 | 4.74E+00 | 2.14E-06 | |
| RI | KLF16.46552.RI | 1.91E-48 | 2.79E-74 | 1.31E-22 | 3.04E+01 | 3.62E+00 | 2.95E-04 |
| RPL13.38091.RI | 2.05E+92 | 1.37E+28 | 3.08E+156 | 7.54E+01 | 2.82E+00 | 4.81E-03 | |
| TIMP1.88928.RI | 1.37E+65 | 2.14E+38 | 8.75E+91 | 3.15E+01 | 4.76E+00 | 1.91E-06 |