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. 2019 Nov 12;10:2578. doi: 10.3389/fmicb.2019.02578

TABLE 4.

Overview of the main characteristics and necessary data for source attribution methods.

Point of attribution Pathogen data Human data Source data




Method Reservoir Exposure Transmission route Risk factor Subtyping Fitness Subtyping Sporadic or epidemic status Exposure & risk factors∗∗ Subtyping Prevalence and exposure∗∗∗ Need to consider all potential sources
Epidemiological (case-control study) No Yes Yes Yes No No No Sporadic Yes No No High
Epidemiological (outbreak investigation) No Yes Yes Yes No No No‡ Epidemic Yes No No High
Microbiological (frequency-matching models) Yes Yes Yes No Yes No‡ Yes Sporadic and epidemic No‡ Yes Yes Medium
Microbiological (population genetics models) Yes Yes Yes No Yes No Yes Sporadic or epidemic No Yes No High
Quantitative exposure/risk assessment Yes Yes Yes Yes No Yes No N/A Yes No Yes Medium
Expert elicitations Yes Yes Yes Yes No No No Sporadic or Epidemic No No No Low

N/A, not applicable. Or amplifying hosts. ∗∗Including travel status. ∗∗∗In this case, food consumption weights. But can be used if available.