TABLE 4.
Point of attribution | Pathogen data | Human data | Source data | |||||||||
Method | Reservoir∗ | Exposure | Transmission route | Risk factor | Subtyping | Fitness | Subtyping | Sporadic or epidemic status | Exposure & risk factors∗∗ | Subtyping | Prevalence and exposure∗∗∗ | Need to consider all potential sources |
Epidemiological (case-control study) | No | Yes | Yes | Yes | No | No | No | Sporadic | Yes | No | No | High |
Epidemiological (outbreak investigation) | No | Yes | Yes | Yes | No | No | No‡ | Epidemic | Yes | No | No | High |
Microbiological (frequency-matching models) | Yes | Yes | Yes | No | Yes | No‡ | Yes | Sporadic and epidemic | No‡ | Yes | Yes | Medium |
Microbiological (population genetics models) | Yes | Yes | Yes | No | Yes | No | Yes | Sporadic or epidemic | No | Yes | No | High |
Quantitative exposure/risk assessment | Yes | Yes | Yes | Yes | No | Yes | No | N/A | Yes | No | Yes | Medium |
Expert elicitations | Yes | Yes | Yes | Yes | No | No | No | Sporadic or Epidemic | No | No | No | Low |
N/A, not applicable. ∗Or amplifying hosts. ∗∗Including travel status. ∗∗∗In this case, food consumption weights. ‡But can be used if available.