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. 2019 Nov 14;25(42):6299–6310. doi: 10.3748/wjg.v25.i42.6299

Figure 2.

Figure 2

lncRNAXLOC_001659 downregulates miR-490-5p expression by binding to the miR-490-5p seed region. A: Bioinformatics analysis showed the binding between lncRNA XLOC_001659 and miR-490-5p seed region; B: Relative luciferase activities of the EC9706 and EC-1 cells co-transfected with lncRNAXLOC_001659-WT or lncRNAXLOC_001659-Mut luciferase reporter vector and miR-NC or MiR-490-5p mimics. aP < 0.05 and bP < 0.01; C: RT-qPCR demonstrated a significant increase in relative miR-490-5p expression in the EC9706 and EC-1 cells after si-Lnc transfection. bP < 0.01.