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PIK3CA is the target gene of miR-490-5p. A: Bioinformatics analysis demonstrated the binding region between miR-490-5p and PIK3CA; B: Relative luciferase activities of the EC9706 and EC-1 cells co-transfected with PIK3CA-WT or PIK3CA-Mut luciferase reporter vector and miR-NC or MiR-490-5p mimics. bP < 0.01; C: MiR-490-5p overexpression inhibited the PIK3CA protein expression in the EC9706 and EC-1 cells.
