Table 6.
MiRNA name | HCC | LC | Fold change | Log2 fold change | P value |
hsa-miR-1 | 0.13 | 0.32 | 0.41 | -1.29 | 0.168 |
hsa-miR-16 | 0.12 | 0.43 | 0.28 | -1.84 | 0.001a |
hsa-miR-21 | 4.21 | 3.82 | 1.10 | 0.14 | 0.801 |
hsa-miR-23b-3p | 0.27 | 0.78 | 0.35 | -1.51 | 0.001a |
hsa-miR-26a | 0.33 | 0.51 | 0.64 | -0.64 | 0.009 |
hsa-miR-29a | 0.54 | 0.42 | 1.29 | 0.37 | 0.001 |
hsa-miR-34-a | 0.69 | 0.16 | 4.31 | 2.11 | 0.001a |
hsa-miR-98 | 1.95 | 1.19 | 1.63 | 0.70 | 0.723 |
hsa-miR-122-5p | 0.12 | 0.98 | 0.12 | -3.06 | 0.001a |
hsa-miR-125b-5p | 0.01 | 0.05 | 0.20 | -2.32 | 0.823 |
hsa-miR-127-3p | 0.29 | 0.78 | 0.37 | -1.43 | 0.059 |
hsa-miR-150-5p | 2.16 | 0.78 | 2.78 | 1.48 | 0.071 |
hsa-miR-185-5p | 0.21 | 0.88 | 0.24 | -2.06 | 0.083 |
hsa-miR-198 | 0.09 | 0.29 | 0.31 | -1.69 | 0.001a |
hsa-miR-199a-3p | 0.08 | 0.31 | 0.26 | -1.94 | 0.001a |
hsa-miR-221 | 9.40 | 3.31 | 2.84 | 1.51 | 0.001a |
hsa-miR-224-5p | 1.82 | 0.71 | 2.56 | 1.36 | 0.021 |
hsa-miR-494-3p | 0.98 | 0.17 | 5.76 | 2.53 | 0.022 |
hsa-miR-877-5p | 1.51 | 0.78 | 1.94 | 0.96 | 0.231 |
hsa-miR-4433b-3 | 1.52 | 0.45 | 3.38 | 1.76 | 0.072 |
Expression data is presented as average fold change = (2-ΔΔCT) in the hepatocellular carcinoma group vs the liver cirrhosis group.
P < 0.005 with ± 1.5 log2 fold expression change. HCC: Hepatocellular carcinoma; LC: Liver cirrhosis; miRNA: MicroRNA.