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. 2019 Oct 25;18(6):4820–4828. doi: 10.3892/etm.2019.8136

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Dexmedetomidine increases the protein levels of survivin in cancer cells following hypoxia insult. (A) Representative western blotting showing the levels of survivin protein expression in the A549 cells. (B) Quantitative analysis of survivin protein expression in the A549 cells. (C) Representative western blotting showing the levels of survivin protein expression in the HCT116 cells. (D) Quantitative analysis of survivin protein expression in the HCT116 cells. The survivin protein expression of the two cells was detected by western blotting and all values are normalized against the N group. *P<0.05 vs. N; ^#P<0.05 vs. H; ⁺P<0.05 vs. HD; n=6 in each group. H, hypoxia; HD, hypoxia + dexmedetomidine; HDA, hypoxia + dexmedetomidine + atipamezole; N, normoxia.