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. 2019 Oct 25;18(6):4820–4828. doi: 10.3892/etm.2019.8136

Figure 4.

Figure 4.

Dexmedetomidine aggravates the hypoxia-induced migratory ability of cancer cells. (A) Representative images showing the migration of the A549 cells. (B) Quantitative analysis of migratory cell number of A549 cells. (C) Representative images showing the migration of the HCT116 cells. (D) Quantitative analysis of migratory cell number of HCT116 cells. The migratory ability of the two cells was detected by Transwell assay. *P<0.05 vs. N; #P<0.05 vs. H; +P<0.05 vs. HD; n = 6 in each group; scale bars represent 50 µm. H, hypoxia; HD, hypoxia + dexmedetomidine; HDA, hypoxia + dexmedetomidine + atipamezole; N, normoxia;