Table 2.
Obstetrically modified SOFA score.
| System Parameter | Score | ||
|---|---|---|---|
| 0 | 1 | 2 | |
| Respiration | |||
| PaO2/FiO2 (mmHg) | ≥400 | 300 to <400 | <300 |
| Coagulation | |||
| Platelets (×106/L) | ≥150 | 100–150 | <100 |
| Liver | |||
| Bilirubin (µmol/L) | ≤20 | 20–32 | >32 |
| Cardiovascular | |||
| Mean arterial pressure (mmHg) | MAP ≥70 | MAP <70 | Vasopressors required |
| Central Nervous System | Alert | Rousable by voice | Rousable by pain |
| Renal | |||
| Creatinine (µmol/L) | ≤90 | 90–120 | >120 |
PaO2 = partial pressure of oxygen; FIO2 = fraction of inspired oxygen (in mmHg, millimetres of mercury, expressed as a decimal); MAP = mean arterial pressure (in mmHg); SOFA = Sequential (sepsis-related) Organ Failure Assessment. Adapted with permission from the SOMANZ guidelines for the investigation and management of sepsis in pregnancy, this table demonstrates a sepsis-related scoring system which uses pregnancy-specific physiological variables to identify the critically ill obstetric patient. In the general population, an acute change in the SOFA score from baseline of ≥2 (where the baseline in the healthy general population can be assumed to be 0 if unknown) has been associated with an increased risk of in-hospital mortality. Further studies are required to ascertain the validity of this data in the obstetric population [35].