Table I.
Levels of H2O2, SOA, and MDA, which is used as an index of LPO, in plasma and placental tissue of NP, HP and RM women.
| Subjects | |||
|---|---|---|---|
| Assayed parameters | NP women (n=28) | HP women (n=28) | RM women (n=28) |
| Plasma H2O2 (nmol/ml) | 7.04±1.12 | 8.11±1.14a | 10.2±1.47b,c |
| Placental tissue H2O2 (nmol/min/mg) | – | 2.41±0.35 | 3.38±0.46d |
| Plasma SOA (nmol/ml) | 30.1±4.50 | 35.3±5.45a | 45.2±6.10b,c |
| Placental tissue SOA (µmol/min/mg) | – | 4.67±0.62 | 5.93±0.78d |
| Plasma MDA (nmol/ml) | 5.03±0.70 | 5.73±0.76a | 7.87±0.96b,c |
| Placental tissue MDA (nmol/g wet weight) | – | 258±35.7 | 334±45.8d |
a
P<0.05, compared with plasma of NP women
b
P<0.0001, compared with plasma of NP women
c
P<0.001, compared with plasma of HP women
d
P<0.0001, compared with placental tissue of HP women. H2O2, hydrogen peroxide; SOA, superoxide anions; MDA, malondialdehyde; LPO, lipid peroxidation; NP, non-pregnant; HP, healthy pregnant; RM, recurrent miscarriage.