Table III.
GSH, GSSG and GSH/GSSG ratio in plasma and placental tissue of NP, HP and RM women.
| Subjects | |||
|---|---|---|---|
| Assayed parameters | NP women (n=28) | HP women (n=28) | RM women (n=28) |
| Plasma GSH (µmol/l) | 2.86±0.30 | 2.51±0.36a | 1.97±0.29b,c |
| Placental tissue GSH (nmol/mg tissue) | – | 6.86±0.95 | 5.40±0.77d |
| Plasma GSSG (µmol/l) | 0.049±0.007 | 0.056±0.008a | 0.071±0.010b,c |
| Placental tissue GSSG (nmol/mg tissue) | – | 0.14±0.018 | 0.18±0.025d |
| Plasma GSH/GSSG | 55.6±6.88 | 48.5±6.61a | 28.8±3.88b,c |
| Placental tissue GSH/GSSG | – | 49.6±6.75 | 31.0±4.19d |
a
P<0.05, compared with plasma of NP women
b
P<0.0001, compared with plasma of NP women
c
P<0.001, compared with plasma of HP women
d
P<0.0001, compared with placental tissue of HP women. GSH, reduced glutathione; GSSG, oxidised glutathione; NP, non-pregnant; HP, healthy pregnant; RM, recurrent miscarriage.