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. 2019 Oct 30;20(21):5417. doi: 10.3390/ijms20215417

Figure 1.

Figure 1

Pivotal TFs regulating β-cell differentiation and maturation in rodents. Schematic representation of the most prominent TFs involved in endocrine induction, lineage specification, differentiation and maturation of β-cells. Gradient colors represent the expression levels during the process. Green colored lines indicate the TFs that are transiently expressed, while the blue ones are those that remain expressed also in adulthood.