. 2019 Oct 30;16(21):4200. doi: 10.3390/ijerph16214200

Table 5.

Distribution of the metabolic biomarker and their Spearman correlations (rho) with THMs

Metabolic Biomarker	Cases (N ^a = 95)	Controls (N = 95)	p ^b	Correlations with THMs
Metabolic Biomarker	Cases (N ^a = 95)	Controls (N = 95)	p ^b	Cr	Cd	Pb	As
Glucose metabolism
FBG (mmol/L); median (IQR)	4.60 (4.30–5.20)	5.13 (4.71–5.73)	<0.001	−0.058	0.048	−0.023	0.039
Lipid metabolism
TG (mmol/L); median (IQR)	1.44 (1.01–2.15)	1.32 (1.02–1.86)	0.455	0.134	0.136	0.065	0.066
TC (mmol/L); median (IQR)	4.13 (3.55–4.66)	4.90 (4.29–5.76)	<0.001	0.045	0.065	−0.100	0.186 *
Liver function
AST (U/L); median (IQR)	17 (15–22)	17 (15–21)	0.610	0.059	−0.138	−0.076	0.002
ALT (U/L); median (IQR)	18 (13–29)	15 (12–20)	0.006	−0.054	−0.132	−0.080	0.046
ALB (g/L); median (IQR)	40.00 (38.00–43.00)	42.12 (39.46–44.89)	<0.001	0.012	0.054	−0.163 *	0.163 *
TP (g/L); median (IQR)	68.00 (64.00–71.00)	69.66 (64.07–76.39)	0.021	0.106	0.100	−0.038	0.208 **
Renal function
BUN (mmol/L); median (IQR)	4.08 (3.37–5.19)	5.24 (4.46–6.45)	<0.001	0.028	−0.042	−0.182 *	0.217 **
CREA (umol/L); median (IQR)	65.00 (57.00–72.00)	64.05 (54.13–73.18)	0.725	0.075	−0.052	−0.207 **	0.014
UA (umol/L); median (IQR)	283.00 (217.00–353.00)	262.00 (221.75–369.25)	0.943	−0.014	−0.094	−0.170 *	0.076

^a Number of subjects. ^b In comparison with the median of controls by Mann-Whitney U test. * p < 0.05. ** p < 0.01. THMs: toxic heavy metals.