ACh |
Acetylcholine |
ACTH |
Adrenocorticotrophic hormone |
AKI |
Acute kidney injury |
Ang |
Angiopoietin |
AP-1 |
Adaptor protein 1 |
APC |
Activated protein C |
ATF6 |
Activating transcription factor 6 |
AVP |
Arginine vasopressin |
C3 |
Complement protein 3 |
C5a |
Complement component 5a |
CAP |
Cholinergic anti-inflammatory pathway |
CHOP |
CEBP homologous protein |
CLP |
Cecal ligation and puncture |
CLRs |
C-type lectin receptors |
Cpb1 |
Carboxypeptidase b1 |
CRP |
C-reaction protein |
DAMPs |
Damage-associated molecular patterns |
DCs |
Dendritic cells |
DIC |
Disseminated intravascular coagulation |
ER |
Endoplasmic reticulum |
ERK1/2 |
Extracellular signal-regulated kinase 1/2 |
ETC |
Electron transfer chain |
FcγR1 |
Fc-γ receptor-1 |
G-CSF |
The cytokines granulocyte colony-stimulating factor |
GM-CSF |
Granulocyte-macrophage colony-stimulating factor |
GRP94 |
Glucose-regulated protein 94 |
HMGB-1 |
High-mobility group box-1 |
HPA |
Hypothalamic-pituitary-adrenal |
IL-1 |
Interleukin-1 |
iNOS |
Inducible nitric oxide synthase |
IRAK-M |
Interleukin-1 receptor-associated kinase-M |
IRE1 |
Inositol-requiring enzyme 1 |
IRF7 |
Interferon regulatory factor 7 |
JNK |
c-Jun N-terminal kinase |
LODS |
Logistic Organ Dysfunction Score |
LPS |
Lipopolysaccharide |
MAPK |
p38 mitogen-activated protein kinase |
MCP-1 |
Monocyte chemoattractant protein-1 |
miRNA |
MicroRNA |
MMPs |
Matrix metalloproteinases |
NA |
Noradrenaline |
NF-κB |
Nuclear factor-κB |
NK cells |
Natural killer cells |
NLRs |
NOD-like receptors |
NRF-1 |
Nuclear respiratory factor-1 |
NS |
Neonatal sepsis |
PAI-1 |
Plasminogen activator inhibitor-1 |
PAMPs |
Pathogen-associated molecular patterns |
PCT |
Procalcitonin |
PD-1/PD-L1 |
Programmed death receptor-1 and programmed death ligand-1 |
PERK |
PKR-like endoplasmic reticulum kinase |
PMX-HP |
Polymyxin B hemoperfusion |
PRRs |
Pattern-recognition receptors |
qSOFA |
Quick Sequential Organ Failure Assessment |
rhAPC |
Recombinant human APC |
RLRs |
RIG-I like receptors |
RNS |
Reactive nitrogen species |
ROS |
Reactive oxygen species |
rTM |
Recombinant TM |
SIGIRR |
Single Ig IL-1R-related molecule |
SIRS |
Systemic Inflammatory Response Syndrome |
SOCS1 |
Suppressor of cytokine signaling 1 |
SOFA |
Sequential Organ Failure Assessment |
ST2 |
Stimulation expressed gene 2 |
sTREM-1 |
Soluble triggering receptor expressed on myeloid cells-1 |
TAK-242 |
Resatorvid |
TFAM |
Transcriptional activator of mitochondrial transcription factor A |
TLRs |
Toll-like receptors |
TM |
Thrombomodulin |
TNF-α |
Tumor necrosis factor-α |
TOLLIP |
Toll interacting protein |
t-PA |
Tissue plasminogen activator |
u-PA |
Urokinase-type plasminogen activator |
α7nAChR |
α7 nicotinic ACh receptor |