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Effect of CHR on TNF-α, IL-6 and IL-1β levels in diabetic mice. Inflammatory cytokine levels in the (A) serum and (B) heart tissue. ##P<0.01 vs. wild group; **P<0.01 vs. C57BL/KsJ-db/db group. Wild, wild-type C57BLKS/J mice; C57BL/KsJ-db/db, spontaneously diabetic mice; CHR, chrysophanol; TNF-α, tumor necrosis factor-α; IL, interleukin.
