| BBB | blood–brain barrier |
| TJ | tight-junction |
| CNS | central nervous system |
| NVU | neurovascular unit |
| CEC | Cerebral endothelial cells |
| ZO-1 | zonula occludens 1 protein |
| MCAO | middle cerebral artery occlusion |
| Aβ | amyloid-beta protein |
| Aβ1-42 | amyloid-beta peptide containing amino acids 1-42 |
| AD | Alzheimer’s disease |
| MMP | matrix metalloproteinase |
| PD | Parkinson’s disease |
| HD | Huntington’s disease |