Table 3.
Multivariate Cox proportional hazard model for risk of major adverse cardiovascular events (MACEs) and all-cause mortality in groups based on short LTLs and high mtDNA4977 deletion.
| MACEs | All-Cause Mortality | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-Value | HR | 95% CI | p-Value | |
| long LTL/low mtDNA4977 (n = 126) |
1.00 | — | 1.00 | — | ||
| long LTL/high mtDNA4977 (n = 76) |
2.3 | 0.9–6.2 | 0.09 | 3.4 | 0.9–12.6 | 0.07 |
| short LTL/low mtDNA4977 (n = 84) |
2.7 | 1.1–7.5 | 0.04 | 2.8 | 0.7–10.4 | 0.12 |
| short LTL/high mtDNA4977 (n = 134) |
4.3 | 1.9–9.6 | 0.0006 | 6.0 | 2.0–18.4 | 0.001 |
Adjusted for age, gender, smoking, hypertension, hypercholesterolemia, diabetes, obesity, multivessel disease, previous MI, previous coronary artery bypass graft, previous percutaneous coronary intervention, creatinine levels, and left ventricular ejection fraction.