Skip to main content
. 2019 Nov 1;20(21):5455. doi: 10.3390/ijms20215455

Figure 9.

Figure 9

Combination of cisplatin and MK-8776 is weakly toxic on uninfected PHK raft cultures. TUNEL assay and γ-H2AX was probed in raft cultures of uninfected PHKs exposed to DMSO, 20 µM cisplatin, 10 µM MK-8776 and combination of cisplatin and MK-8776, both at 10 µM, from days 9 to 12 before harvest. Images were captured with 20× objective. Note that the epithelium was thinner in all three treatments attributed to a blockade of basal cell proliferation. However, there is hardly any γ-H2AX induction or TUNEL signals.