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. 2019 Oct 30;20(21):5415. doi: 10.3390/ijms20215415

Figure 4.

Figure 4

PFKFB3 inhibition lessens Oxa-induced autophagy. (a,b) Cell lysates were subjected to immunoblotting following treatment of SW480 cells with Oxa, or together with PFK-15 (6 μM; unless otherwise indicated) in the presence or absence of CQ for 2 h. (c,d) SW480 cells were transfected with the PFKFB3 siRNA or control siRNA (mock) for 48 h. Cell lysates were collected and subjected to immunoblotting following treatment with Oxa in the presence or absence of CQ for 2 h. All data were acquired from at least three independent experiments.